SIGNATRET MICROSPHARE 0.05%

Package	Per tube	Savings	Price
10 tube	$1.80	$6	$24 $18
8 tube	$1.88	$5	$20 $15
6 tube	$2.17	$3	$16 $13
4 tube	$2.50	$2	$12 $10
2 tube	$3.50	$1	$8 $7
1 tube	$4.00	–	$4

What is this medicine?

TRETINOIN is a form of vitamin A used to treat acne. This specific formulation (microsphere 0.05% gel) is designed to release tretinoin slowly, which can reduce irritation. It promotes cell turnover and helps keep pores clear. It may also be used to improve the appearance of skin damaged by the sun, such as fine wrinkles, roughness, and dark spots.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

Eczema or very sensitive skin
Sunburn, windburn, or broken skin
Rosacea or other chronic skin inflammation
Skin cancer or a history of skin tumors
If you’re using other topical treatments on your face
An unusual or allergic reaction to tretinoin, retinoids, vitamin A products, or any ingredients in the gel
Pregnant or trying to get pregnant
Breast-feeding

How should I use this medicine?

Use this medicine on the skin only.

Wash your hands before and after applying.
Cleanse your skin with a mild soap and allow it to dry for 20–30 minutes before application.
Apply a pea-sized amount once daily at bedtime. Spread a thin layer over the affected area.
Avoid contact with eyes, lips, nostrils, or mucous membranes.
Do not use more than prescribed; excessive use increases the risk of skin irritation without improving effectiveness.

Overdosage: This medicine is for external use only. If accidentally swallowed, contact a poison control center or emergency room immediately.

What if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is near the time of your next dose, skip the missed dose and resume your regular schedule. Do not apply double or extra doses.

What may interact with this medicine?

Skin products that cause dryness or irritation (astringents, abrasive cleansers, alcohol-containing products)
Medications containing benzoyl peroxide, salicylic acid, sulfur, or resorcinol
Other acne medications unless directed by your doctor
Drugs that increase sensitivity to sunlight (e.g., tetracyclines, fluoroquinolones, thiazides)

This list may not describe all possible interactions. Give your health care provider a full list of all medicines, herbs, non-prescription products, and skincare items you use.

What should I watch for while using this medicine?

Acne may appear to worsen at first before it improves (usually within the first few weeks).
Use sunscreen (SPF 30 or higher) and protective clothing while using this medication.
Avoid direct sunlight, sunlamps, and tanning beds.
Moisturizers may be used to reduce dryness and peeling.
Do not use other potentially irritating products unless advised by your doctor.
Avoid waxing or laser treatments in the application area.
If you become pregnant or plan to, inform your doctor promptly.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

Severe burning, redness, crusting, or swelling of treated skin
Rash, blistering, or severe irritation
Signs of allergic reaction (rash, itching/swelling, dizziness, difficulty breathing)

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

Mild redness or peeling
Dryness or flaking of the skin
Temporary worsening of acne
Mild burning, stinging, or itching

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).
Keep tightly closed and protect from light and moisture.
Do not freeze.
Discard any unused gel after the expiration date.

SIGNATRET MICROSPHARE 0.05%