KOLCHISMART

KOLCHISMART 0.5mg

What is this medicine?

KOLCHISMART 0.5 MG contains Colchicine, which is used to treat and prevent gout attacks (a type of arthritis caused by too much uric acid in the blood). It works by reducing inflammation and decreasing the build-up of uric acid crystals in joints. It may also be used to treat familial Mediterranean fever (FMF), a genetic inflammatory disorder.

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What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• Kidney or liver disease

• Heart disease

• Gastrointestinal disease (especially ulcers or bleeding)

• Blood disorders

• If you are elderly or debilitated

• An unusual or allergic reaction to colchicine or other medicines, foods, dyes, or preservatives

• Pregnant or trying to get pregnant

• Breast-feeding

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How should I use this medicine?

Take this medicine by mouth with a full glass of water. It can be taken with or without food to reduce stomach upset. Follow the directions on your prescription label exactly. Do not take more often than prescribed.

Overdosage: Colchicine overdose can be fatal. If you think you have taken too much of this medicine, seek emergency medical help immediately.

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What if I miss a dose?

If you miss a dose, take it as soon as possible. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

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What may interact with this medicine?

• Clarithromycin, erythromycin or other macrolide antibiotics

• Cyclosporine

• Digoxin

• Statins (like atorvastatin, simvastatin)

• Antifungals like ketoconazole or itraconazole

• HIV protease inhibitors (like ritonavir)

• Grapefruit juice

This list may not describe all possible interactions. Tell your health care provider about all the medicines, herbs, non-prescription drugs, and dietary supplements you use. Also let them know if you smoke, drink alcohol, or use recreational drugs.

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What should I watch for while using this medicine?

• Keep regular appointments with your doctor to monitor response and side effects.

• Report signs of toxicity immediately (e.g., vomiting, diarrhea, muscle pain, numbness).

• Avoid alcohol while using this medicine, as it can worsen gout symptoms.

• Do not exceed the prescribed dose.

• Inform your doctor if you develop symptoms of infection, unusual bleeding, or weakness.

Women who are pregnant or may become pregnant should talk to their doctor about the risks of taking colchicine. Colchicine may pass into breast milk—consult your doctor before breastfeeding.

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What side effects may I notice from this medicine?

Serious side effects – report immediately:

• Severe diarrhea or vomiting

• Muscle pain or weakness

• Numbness or tingling in fingers or toes

• Unusual bruising or bleeding

• Signs of infection (fever, sore throat)

• Blood in urine or stools

Common side effects – may not need medical attention (report if bothersome):

• Nausea

• Mild stomach pain

• Diarrhea

• Headache

This list may not include all possible side effects. Contact your healthcare provider for medical advice about side effects.

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Where should I keep my medicine?

• Keep out of the reach of children.

• Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).

• Protect from moisture and light.

• Do not use after the expiration date.

• Safely discard any unused medicine.