KOLCHISMART

KOLCHISMART 1.2mg

What is this medicine?

COLCHICINE (brand: Kolchismart) is an anti-inflammatory medication traditionally derived from the autumn crocus. It’s used to treat and prevent gout attacks, manage familial Mediterranean fever (FMF), and may reduce complications from coronary artery disease (CAD) .

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What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• Liver or kidney disease

• Blood disorders (e.g., low white cell or platelet counts)

• Muscle disorders or are taking statins/other drugs that affect muscles

• Allergic reactions to colchicine or similar medications

• Pregnancy or trying to get pregnant

• Breast‑feeding

• If you’re using drugs that interact with colchicine, such as certain antibiotics, antifungals, HIV protease inhibitors, or grapefruit juice

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How should I use this medicine?

• For a gout flare: 1.2 mg (typically two 0.6 mg tablets) at first sign, followed by 0.6 mg one hour later. Do not exceed 1.8 mg over 1 hour, and wait at least 3 days before repeating .

• For prevention of gout: 0.6 mg once or twice daily (max 1.2 mg/day) .

• For FMF: 1.2–2.4 mg per day (one or two divided doses) .

• Take by mouth, with or without food. Drink plenty of water.

• Overdose: If you suspect overdose, seek emergency medical help immediately—colchicine has a narrow safety margin.

• Note: This medicine is only for you; do not share it.

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What if I miss a dose?

• For flare treatment: If you miss the first dose, take it ASAP, then the second dose one hour later. If near next planned dose, skip the missed dose.

• For prevention/FMF: Take when remembered, unless close to the next scheduled dose—then skip and continue normal schedule. Do not double doses

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What may interact with this medicine?

• Major interactions:

  • Antibiotics (e.g., clarithromycin)

  • Antifungals (e.g., ketoconazole)

  • HIV protease inhibitors (e.g., ritonavir, atazanavir)

  • Grapefruit or grapefruit juice

• Others: statins, fibrates, digoxin, verapamil/diltiazem; risk of toxicity via muscle or GI issues

• Always tell your healthcare provider about all medications, supplements, alcohol, or smoking.

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What should I watch for while using this medicine?

• Have regular blood tests to monitor kidney, liver, and blood counts .

• Stop and seek help if you experience:

  • Severe diarrhea, vomiting, abdominal pain

  • Muscle weakness or pain, numbness or tingling

  • Signs of infection (fever, chills), unusual bleeding or bruising

• Alert your doctor if pregnant, planning pregnancy, or breastfeeding.

• Avoid grapefruit products.

• Stay hydrated, especially if diarrhea or vomiting occurs.

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What side effects may I notice from this medicine?

Serious – report immediately:

• Severe GI distress (diarrhea, vomiting, stomach pain)

• Muscle weakness, muscle pain, numbness/tingling

• Unusual bleeding/bruising, signs of infection (fever)

• Allergic reactions (rash, swelling, difficulty breathing)

Less serious – tell your doctor if bothersome:

• Diarrhea, nausea, vomiting, abdominal cramps

• Mild headache or sore throat

• Hair thinning (rare)

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Where should I keep my medicine?

• Keep out of reach of children.

• Store at room temperature, ideally 20–25 °C (68–77 °F); short period up to 30 °C (86 °F) is acceptable .

• Protect from moisture and light.

• Discard unused medicine after its expiration date.