LODONAK 3mg
| Package | Per tablet | Savings | Price |
|---|---|---|---|
| 180 tablets | $0.21 | $12.40 | $50.40 $38 |
| 150 tablets | $0.21 | $10 | $42 $32 |
| 120 tablets | $0.22 | $7.60 | $33.6 $26 |
| 90 tablets | $0.23 | $4.20 | $25.2 $21 |
| 60 tablets | $0.25 | $1.80 | $16.8 $15 |
| 30 tablets | $0.30 | – | $8.40 |
What is this medicine?
Lodonak 3 mg contains naltrexone, an opioid antagonist. It’s primarily used in medication-assisted treatment for alcohol dependence and opioid dependence, helping reduce cravings and block the euphoric effects if relapse occurs. At this lower dose, it may also be used off-label for chronic pain or inflammation in conditions like fibromyalgia or multiple sclerosis.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these:
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Liver disease or impaired liver function, as naltrexone can cause hepatotoxicity.
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Current opioid use—you must be opioid-free (usually 7–10 days) before starting to avoid precipitating withdrawal.
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Kidney disease or other severe medical conditions—dose adjustments or caution may be required.
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Allergy to naltrexone or naloxone.
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Pregnant or breastfeeding, as safety in these groups is unclear.
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Upcoming surgery—discontinue naltrexone about 7 days before a planned procedure.
How should I use this medicine?
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Take 3 mg orally once daily, with or without food. Swallow whole—do not crush or chew.
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It may take several weeks to notice benefits in cravings or pain relief (if using off-label).
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Do not stop abruptly without consulting your provider to avoid relapse or withdrawal.
Overdose: If you believe you’ve taken too much, seek emergency medical attention immediately.
Missed dose: Take once remembered, unless it’s close to your next scheduled dose—then skip the missed dose. Do not double up.
What may interact with this medicine?
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Opioids—will be blocked and may trigger withdrawal.
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CYP-metabolized medications—CYP inhibitors can affect naltrexone levels.
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CNS depressants—such as alcohol or sedative medications.
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Herbal supplements, particularly opioid-related ones like St. John’s wort.
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Always inform your provider of all medications, supplements, or herbal products you’re taking.
What should I watch for while using this medicine?
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Liver function tests recommended periodically due to potential hepatotoxicity.
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Avoid opioids or alcohol while taking Lodonak.
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Pregnant women should avoid handling broken or crushed capsules.
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Watch for liver injury signs: dark urine, yellowing of eyes/skin, abdominal pain.
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Monitor mental health: depression or suicidal thoughts may occur.
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Be cautious when donating blood during and for some time after treatment.
What side effects may I notice from this medicine?
Report immediately:
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Signs of liver injury (jaundice, dark urine, upper abdominal pain).
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Severe allergic reactions (rash, swelling, breathing difficulty).
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Severe mood changes, depression, suicidal thoughts.
Common (usually mild):
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Difficulty sleeping or vivid dreams
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Nausea, vomiting, abdominal cramps
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Headache, dizziness, anxiety
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Muscle/joint pain, fatigue, decreased appetite
Rare/serious:
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Severe liver dysfunction, injection reactions (if using injectables), increased risk of opioid overdose if opioids are taken after stopping naltrexone
Where should I keep my medicine?
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Store in a cool, dry place at 20–25 °C (68–77 °F); brief exposures to 15–30 °C are acceptable.
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Keep away from moisture, heat, and direct sunlight.
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Keep out of reach of children.
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Do not use after the expiration date.
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Do not crush or open capsules—swallow whole.