A-RET Gel 0.1% 20 GM

What is this medicine?

A-RET Gel contains Tretinoin, a topical retinoid (vitamin A derivative) used to treat acne vulgaris and improve the appearance of skin affected by sun damage and uneven pigmentation.

Tretinoin works by increasing the turnover of skin cells, preventing clogged pores, reducing acne lesions, and promoting the growth of healthy new skin. The 0.01% strength is the lowest concentration and is often recommended for patients with sensitive skin or those beginning tretinoin therapy.

This medicine may be used for:

• acne vulgaris (pimples)

• blackheads and whiteheads

• mild hyperpigmentation

• rough skin texture

• photoaged skin with fine wrinkles (as directed by a healthcare professional)

This medicine is for external use only.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• eczema

• severe skin irritation

• sunburn

• sensitive skin

• rosacea

• skin infections

• allergy to tretinoin, vitamin A products, or any ingredients in the gel

• history of severe reactions to topical medicines

• pregnant or trying to get pregnant

• breast-feeding

Tell your healthcare provider about all prescription medicines, over-the-counter medicines, herbal products, and skin care products you are currently using.

How should I use this medicine?

This medicine is for external use only.

Wash your hands before and after application.

Cleanse the affected area with a mild cleanser and allow the skin to dry completely before applying the gel.

Apply a thin layer once daily, preferably at bedtime, or as directed by your healthcare provider.

Use only enough gel to lightly cover the affected area.

Avoid contact with:

• eyes

• lips

• inside the nose

• mouth

• broken, irritated, or sunburned skin

Use sunscreen and wear protective clothing during treatment because tretinoin increases skin sensitivity to sunlight.

Overdosage: Excessive application may result in severe redness, peeling, burning, or irritation. If accidentally swallowed, contact a poison control center or emergency room immediately.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss an application, apply it when you remember.

If it is nearly time for your next scheduled application, skip the missed dose.

Do not apply extra gel to make up for the missed application.

What may interact with this medicine?

• benzoyl peroxide (unless directed by your healthcare provider)

• salicylic acid preparations

• sulfur-containing acne products

• resorcinol

• medicated soaps and cleansers

• alcohol-containing skin products

• abrasive cosmetic products

• topical antibiotics

• other topical retinoids

This list may not describe all possible interactions. Inform your healthcare provider about all medicines and skin care products you use.

What should I watch for while using this medicine?

Visit your healthcare provider for regular evaluation of your treatment.

Acne may temporarily worsen during the first few weeks before improvement occurs.

Protect treated skin from excessive sunlight, tanning beds, and UV lamps.

Apply a gentle moisturizer if dryness or peeling becomes uncomfortable.

Avoid waxing, laser treatments, dermabrasion, or chemical peels unless approved by your healthcare provider.

Contact your doctor if severe redness, blistering, swelling, or allergic reactions develop.

Women should notify their healthcare provider immediately if pregnancy occurs during treatment.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions such as rash, itching, hives, swelling of the face, lips, tongue, or throat

• severe redness

• blistering

• severe burning or stinging

• swelling of the treated area

• difficulty breathing

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• mild redness

• dryness

• peeling

• itching

• mild burning sensation

• increased sensitivity to sunlight

• temporary worsening of acne

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).

Protect from heat, moisture, and direct sunlight.

Keep the tube tightly closed when not in use.

Do not freeze.

Throw away any unused medicine after the expiration date.